physician photo

Corey R. Deeken, PhD

  • Instructor of Surgery
  • Director of Biomedical Engineering and Biomaterials Laboratory

Graduate School

Doctor of Philosophy in Biological Engineering
University of Missouri, Columbia, Missouri, 2008
Emphasis Area: Biomedical Engineering/Biomaterials

Fellowships
2006-2008, National Science Foundation Graduate Research Fellowship
University of Missouri-Columbia, Columbia, Missouri
2005-2006, National Science Foundation Grades K-12 Teaching Fellowship

Research Interests

  • Characterization of synthetic and biologic tissue-based scaffold materials, particularly those used for hernia repair

  • Evaluation of the integration and remodeling of biologic tissue-based scaffold materials

  • Effects of processing conditions (decellularization, crosslinking, sterilization) on the properties of biologic tissue-based scaffold materials

  • Methods for fixation of hernia repair materials (sutures, tacks, glues, etc.)

  • Mechanical testing of pristine or explanted scaffolds (uniaxial tensile testing, T-Peel testing, ball-burst compression testing)

  • Development of novel scaffold materials


  • Contact Information

    Laboratory/Office Address:
    3347 Clinical Sciences Research Building (CSRB)
    St. Louis, MO 63110
    Phone: 314-362-9520
    Email: deekenc@wudosis.wustl.edu

    Selected Publications

    Lerdsirisopon S, Frisella MM, Matthews BD, Deeken CR. Biomechanical evaluation of potential damage to hernia repair materials due to fixation with helical titanium tacks. Surg Endosc, e-pub 13 July 2011.

    Eliason BJ, Frisella MM, Matthews BD, Deeken CR. Effect of repetitive loading on the mechanical properties of synthetic hernia repair materials. J Am Coll Surg, e-pub 25 June 2011.

    Jenkins ED, Lerdsirisopon S, Costello KP, Melman L, Greco SC, Frisella MM, Matthews BD, Deeken CR. Laparoscopic fixation of biologic mesh at the hiatus with fibrin or polyethylene glycol (PEG) sealant in a porcine model. Surg Endosc, e-pub 19 May 2011.

    Deeken CR, Melman L, Jenkins ED, Greco SC, Frisella MM, Matthews BD. Histologic and biomechanical evaluation of crosslinked and non-crosslinked biologic meshes in a porcine model of ventral hernia repair. J Am Coll Surg. 2011;212:880-888.

    Jenkins ED, Melman L, Deeken CR, Greco SC, Frisella MM, Matthews BD. Biomechanical and histological evaluation of fenestrated and non-fenestrated biologic mesh in a porcine model of ventral hernia repair. J Am Coll Surg. 2011 Mar; 212(3: 327-399.

    Deeken CR, Fox DB, Bachman SL, Ramshaw BJ, Grant SA. Characterization of bionanocomposite scaffolds comprised of amine-functionalized gold nanoparticles and silicon carbide nanowires crosslinked to an acellular porcine tendon. J Biomed Mater Research: Part B. 2011 May;97B:334-344.

    Deeken CR, Cozad MJ, Bachman SL, Ramshaw BJ, Grant SA. Characterization of bionanocomposite scaffolds comprised of amine-functionalized single-walled carbon nanotubes crosslinked to an acellular porcine tendon. J Biomed Mater Research: Part A. 2011 Mar;96(3):584-594.

    Brown SR, Melman L, Jenkins ED, Deeken CR, Frisella MM, Brunt LM, Eagon JC, Matthews BD. Collagen type I:III ratio of the gastroesophageal junction in patients with paraesophageal hernias. Surg Endosc. 2011;25:1390-1394.

    Deeken CR, Abdo MS, Frisella MM, Matthews BD. Physicomechanical evaluation of polypropylene, polyester, and polytetrafluoroethylene meshes for inguinal hernia repair. J Am Coll Surg. 2011 Jan;212(1):68-79.

    Deeken CR, Abdo MS, Frisella MM, Matthews BD. Physicomechanical evaluation of absorbable and nonabsorbable barrier composite meshes for laparoscopic ventral hernia repair. Surg Endosc. 2011;25:1541-1552.

    Deeken CR, White AK, Bachman SL, Ramshaw BJ, Cleveland DS, Loy TS, Grant SA. Method of preparing a decellularized porcine tendon using tributyl phosphate. J Biomed Mater Research: Part B. 2011 Feb;96B(2):199-206.

    Deeken CR, Esebua M, Bachman SL, Ramshaw BJ, Grant SA. Assessment of the biocompatibility of two novel, bionanocomposite scaffolds in a rodent model. J Biomed Mater Research: Part B. 2011 Feb;96B(2):351-359.

    Melman L, Jenkins ED, Deeken CR, Brodt MD, Brown SR, Brunt LM, Eagon JC, Frisella MM, Matthews BD. Evaluation of acute fixation strength for mechanical tacking devices and fibrin sealant versus polypropylene suture for laparoscopic ventral hernia repair. Surg Innov. 2010 Dec;17(4):285-290,

    Jenkins ED, Melman L, Frisella MM, Deeken CR, Matthews BD. Evaluation of acute fixation strength of absorbable and nonabsorbable barrier coated mesh secured with fibrin sealant. Hernia. 2010 Oct;14(5):505-509.

    Costello CR, Bachman SL, Ramshaw BJ, Grant SA Materials characterization of explanted polypropylene hernia meshes. J of Biomed Mater Res Part B. 2007 Oct;83B(1):44-49.

    Click here  for a link to Dr. Deeken's Pub Med Page of publications.